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Clínica de Epilepsia | Trabalhos na Íntegra

Unilateral topical cortical application of penicillin: electrographic aspects. A new complement to an old model.

Cukiert A1, Baumel SW, Andrioli MS, Marino R Jr.


In 7 cats 800 IU of penicillin were applied diffusely over one hemisphere on the exposed neocortex. After 40 min all animals showed bilateral and synchronous burst discharges with a higher amplitude at the hemisphere where the penicillin had been applied. These data fill a gap in the literature concerning feline generalized penicillin epilepsy, in which penicillin is applied bilaterally on the exposed neocortex.